徐华栋老师课题组在Organic Chemistry Frontiers发表研究论文

发布时间:2017-07-08浏览次数:44

Straightforward regioselective construction of 3,4-dihydro-2H-1,4-thiazine by rhodium catalysed [3+3] cycloaddition of thiirane with 1-sulfonyl-1,2,3-triazole: a pronounced acid additive effect

Xiao-Long Lu, Ya-Ting Liu, Qing-Xia Wang, Dr. Mei-Hua Shen and Dr. Hua-Dong Xu

  

Article first published online: 30 MAR 2016 | DOI: 10.1039/c6qo00084c

全文键连: http://pubs.rsc.org/en/content/articlelanding/2016/qo/c6qo00084c#!divAbstract

  

Abstract: A rhodium catalyzed regioselective coupling of thiirane with 1-sulfonyl-1,2,3-triazole has been realized to give a formal [3+3] cycloaddition product 3,4-dihydro-2H-1,4-thiazine via the 1,3-insertion model of azavinyl carbene. An acetic acid additive is used to improve the reaction in terms of both yield and rate.