王建浩 简介

发布时间:2017-05-15浏览次数:105

王建浩博士/副教授/硕士生导师

863计划青年科学家(2014

江苏省六大人才高峰C类(2014

江苏省333工程第三层次(2016

联系方式:

常州大学制药与生命科学学院

江苏省常州市武进科教城天润科技大厦A617 邮编213164

Email: minuswan#cczu.edu.cnminuswan#gmail.com

  

招生方向:生物化工、制药工程

  

讲授课程:药物分析、药物分析实验、仪器分析

  

王建浩,山东威海人,生物医学工程博士,2015年被评为首届常州大学青年标兵。研究方向:纳米生物分析化学、生物材料及纳米医药,主要包括纳米荧光标记技术,基于纳米荧光的生物传感技术,基于纳米粒子的肿瘤早期检测与治疗研究,荧光毛细管电泳生物分析,靶向多肽合成及蛋白与多肽相互作用等。主持863、国家自然基金等多个项目,发表SCI收录论文60多篇,申请专利30多项。担任国际期刊CurrentUpdates in NanotechnologyInsightsin Biomedical Engineering编委。

  

主持项目:

1. 科技部863计划青年科学家专题,基于纳米技术的结肠癌早期检测与治疗研究(2014AA020521),2014-2016115万,主持人

2. 国家自然基金(81201085),基于靶向TCP-1多肽的多功能超顺磁氧化铁纳米粒子用于结肠癌早期诊断和治疗的研究 2013-2015年,23万,主持人

3. 国家自然基金面上项目(81473269),TCP-1 靶向多肽在胃癌肿瘤血管上的特异靶点鉴定及其靶向传输抗肿瘤药物的研究,50万,2015-2018,共同主持

4.国家自然基金海外及港澳学者合作研究基金项目 (21628201), 基于纳米颗粒的多酶组装,20万,2017-2018,共同主持

5. 国家自然基金对外合作与交流 (81310108019)2013年,多功能纳米材料SPIO-TCP-1-Dox的体外生物学评价研究1.5万,主持人(已结题)

6.江苏省自然科学基金(BK20141170),化学与生物逻辑开关控制的自陈式探针与药物释放研究,10万,主持人

7.常州市国际合作项目(CZ20160015),基于谷胱甘肽诱导的“TCP-1单功能化—Nanobelt单标记可控载药的纳米载药系统研究,10万,2016-2018,主持人

8. 常州市科技支撑计划(社会发展)资助项目(CE20125052),2012-2014年,结肠癌肿瘤靶向金纳米粒子介导的新型给药系统研究,10万,主持人(已结题)

9. 常州大学博士基金,2011-2013年,3万,主持人(已结题)

  

指导学生项目:

2014年江苏省普通高校学术学位研究生科研创新计划项目(研究生)

2015年全国大学生创新计划项目(本科)

2015年江苏省大学生创新计划项目(本科)

  

学习及工作经历:

2011.11-至今常州大学制药与生命学院副教授

2009.7-2011.11香港中文大学化学系博士后

2004.9-2009.6华中科技大学生命科学与技术学院博士

2000.9-2004.6华中科技大学生命科学与技术学院本科

  

发表论文及专利:

已发表SCI论文64篇,其中以第一作者及通讯作者发表SCI论文38篇。

  

2017- present

64. Wang JFan JLi JLiu LWang JJiang PLiu XQiu L.In-capillary probing of quantum dots and fluorescent protein self-assembly and displacementusing Försterresonance energy transfer. J Sep Sci. 2017, doi:10.1002/jssc.201600937.

63. Qin HJiang XFan JWang JLiu LQiu LWang J*, Jiang P*. Investigation ofthe weak binding of a tetrahistidine-tagged peptide to quantum dots byusing capillary electrophoresis with fluorescence detection.J Sep Sci. 2017, doi:10.1002/jssc.201601183.

  

2016-

62. Wang JYang LLiu LWu HWang JJiang PJiang XQiu L.Investigationof multivalent interactions between conjugate of quantum dots with c-Mycpeptide tag and the anti-c-Myc antibody by capillary electrophoresis withfluorescence detection. J Sep Sci. 2016; 39(23):4653-4659.

61. JianhaoWang, Yuqin Qin, Shi-Wen Jiang, Li Liu, Yao Lu, Jinping Li *, Lin Qiu*, andPengju Jiang*, Fluorescence coupled in-capillary DNA hybridization assay andits application to identification of DNA point mutation, Sensors andActuators B: Chemical, 2016, 237: 106–112.

60. Feifei Liu, Jianhao Wang*, Li Yang, Li Liu, Shumin Ding, Minli Fu, Linhong Dengand Li-qian Gao, Developing a fluorescence coupled capillary electrophoresisbased method to probe interactions between QDs and colorectal cancer-targetingpeptides, Electrophoresis2016, 37, 2170–2174.

59. JianhaoWang, Chencheng Zhang, Li Liu, Karunakaran A. Kalesh, Lin Qiu, Shumin Ding,Minli Fu, Li-qian Gao and Pengju Jiang, A capillary electrophoresis method toexplore the self-assembly of a novel polypeptide ligand with quantum dots, Electrophoresis2016, 37, 2156–2162.

58. JianhaoWang, Yuqin Qin, Haifang Qin, Li Liu, Shumin Ding, Yiwan Teng, Junling Ji, LinQiu*, and Pengju Jiang*, Simultaneous detection of assembly and disassembly ofmultivalent HA tag and anti-HA antibody in single in-capillary assay, Electrophoresis2016,37, 2163–2169.

57. PeilinGuo, Jie Fan, Yongjiang Cheng, JianhaoWang*, Cheli Wang*, Characterization of the Self-Assembly of GlutathioneStabilized Cadmium Selenide-Zinc Sulfide Quantum Dots with a Cyanine5 LabeledPeptide by Capillary Electrophoresis and Fluorescence, Analytical Letters, 2016, DOI:10.1080/00032719.2016.1171328.

56. JianhaoWang, JinchenLi, Jianpeng Wang, Li Liu, Jinping Li, Haifang Qin, Shumin Ding, Minli Fu, JunlingJi, Pengju Jiang*, Lin Qiu*, Simultaneous monitoring of quantum dots and theirassembly and disassembly with PreScission protease using capillaryelectrophoresis with fluorescence detection, Journal of Separation Science, 2016, 39(9):1785-1791.

55. Jianhao WangYuqin QinJinchen LiXiang ZhouYi YaoCheli WangLin Qiu*, Pengju Jiang*,Försterresonance energy transfer analysis of quantum dots and peptide self-assemblyinside a capillary,Sensors andActuators B: Chemical, 2016, 227: 619–625.

54. Yuqin Qin1Lin Qiu1Haifang QinShumin DingLi LiuYiwan TengYao ChenCheli WangJinchen Li,Jianhao Wang*, Pengju Jiang*, In-capillarydetection of fast antibody-peptide binding usingfluorescence coupled capillary electrophoresis, Electrophoresis 2016, 37: 233-238.

53. Wang JLi JWang JWang CTeng TChen YLi JDong BQiu L*, Jiang P*.Online probing quantum dots and engineered enzyme self-assembly in a nanoliterscale. Electrophoresis 2016,37, 438–443. (SCI, IF 3.028)

52. JianhaoWang, Jingyan Li, Yiwan Teng, Yanhua Bi, Wei Hu, Jinchen Li, Cheli Wang,Lin Qiu*, and Pengju Jiang*, Charge Effect on the Quantum Dots-Peptide Self-AssemblyUsing Fluorescence Coupled Capillary Electrophoresis, Journal of Nanoscience and Nanotechnology, 2016, 16,4035-4039 (SCI, IF 1.556)

51. Lu QChen HSenkowski CWang JWang XBrower SGlasgow WByck DJiang SW*, Li J.*RecombinantHE4 protein promotes proliferation of pancreatic and endometrial cancer cell lines.Oncol Rep.2016; 35(1):163-170.

  

2015-

50. Jianhao Wang,Jingyan LiJinchen LiFeifei LiuXiang ZhouYi YaoCheli WangLin Qiu*, Pengju Jiang*,In-capillary self-assembly and proteolytic cleavage of polyhistidine peptidecapped quantum dots,Analytica Chimica Acta,2015, 895:112-117. (SCI, IF 4.513)

49. JianhaoWang, JinchenLi, Chencheng Zhang, Jie Fan, Li Yang, YaqinGu, Feifei Liu, Cheli Wang, Bingyu Dong, Lin Qiu* and PengjuJiang*, In-capillary probing QDs and HAT tag self-assembly and displacement usingFörster resonance energy transfer, Electrophoresis2015, 36:2636-2641. (SCI, IF 3.028)

48. Wang JLi JLi JQin YWang CQiu L*, Jiang P*.In-capillary self-assembly study of quantum dots and protein using fluorescencecoupled capillary electrophoresis. Electrophoresis2015;36(14):1523-1528. (SCI, IF 3.028)

47. Wang JLi JChen YTeng YWang CLi JLiu LDong BQiu L*, Jiang P.*Capillary electrophoretic studies on quantum dots and histidine appendedpeptides self-assembly. Electrophoresis 2015;36(19):2419-2424. (SCI, IF 3.028)

46. JianhaoWang, Jingyan Li, Jinchen Li, Feifei Liu, Yaqin Gu, Jie Fan, Bingyu Dong,Cheli Wang, Lin Qiu*, Liqian Gao*, Su Seong Lee*, Pengju Jiang*, Organic Chemistry Tool for Nanoparticles Monofunctinalizationand Their Biomedical ApplicationsCurrentOrganic Chemistry, 2016, 20, 1786-1796 (SCI, IF2.157)

45. Qiu L, Li J, Qin Y, Zhang C, Jiang P*, WangJ*.Capillary electrophoretic studies on quantum dots and Hisn-appended peptidesself-assembly. Nanomedicine: Nanotechnology,Biology and Medicine, 2016, 12 488-488. (International Conferenceon Nanomedicine and NanoBiotechnology, SCI, IF: 6.155)

44. Wang J,Li J, Li J, Wang C, Qiu L*, Jiang P*. In-capillary self-assembly study of quantumdots and peptide using fluorescence coupled capillary electrophoresis. Nanomedicine: Nanotechnology, Biologyand Medicine, 2016, 12, 514-514 (International Conference onNanomedicine and NanoBiotechnology, SCI, IF: 6.155)

43. Wang J,Li J, Li J, Wang C, Qiu L*, Jiang P*. In-capillary study of Förster resonanceenergy transfer between quantum dots and ATTO 590-peptide using fluorescencecoupled capillary electrophoresis.Nanomedicine:Nanotechnology, Biology and Medicine, 2016, 12, 515-515. (InternationalConference on Nanomedicine and NanoBiotechnology, SCI, IF: 6.155)

42. Lu QLi JSenkowski CTang ZWang JHuang TWang XTerry KBrower SGlasgow WChen H*, Jiang SW*.Promoter Hypermethylation and Decreased Expression of Syncytin-1 in PancreaticAdenocarcinomas. PLoS One. 2015;10(7):e01 34412. (SCI, IF 3.234)

41. Cai GHLi MXLu LYi Chan RLWang JHCho CH*.Thecurrent role and therapeutic targets of vitamin D in gastrointestinalinflammation and cancer. Curr Pharm Des. 2015;21(21):2917-23. (SCI, IF 3.452)

  

Before 2015

40. Jianhao Wang1, Pengju Jiang1, ZuoyanHan, Lin Qiu, Cheli Wang, Bo Zheng, and Jiang Xia*, Fast Self-Assembly Kineticsof Quantum Dots and a Dendrimeric Peptide Ligand, Langmuir, 2012, 28:7962–7966. (SCI, IF 4.186)

39. Jian-HaoWang, Jiang Xia*, Preferential Binding of a Novel Polyhistidine PeptideDendrimer Ligand on Quantum Dots Probed by Capillary Electrophoresis, Analytical Chemistry, 2011, 83: 6323–6329. (SCI, IF5.856)

38. Jian-HaoWang*, Jiang Xia*, Capillary electrophoretic studies on displacement andproteolytic cleavage of surface bound oligohistidine peptide on quantum dots, AnalyticaChimica Acta, 2012, 709: 120–127. (SCI, IF 4.555)

37. Jian-Hao Wang, Yanan Yue, Gaojian Chen and Jiang Xia*,Protease-Promoted Drug Delivery Using Peptide-Functionalized GoldNanoparticles, Soft Matter,2011, 7: 7217–7222. (SCI, IF 4.39)

36. Jian-HaoWang1, Xi Jin1, Jia-hui Liu, Chaitan Khosla*, JiangXia*, Resolving multiple protein-peptide binding events: implication forHLA-DQ2 mediated antigen presentation in celiac disease, Chem-Asian J, 2012, 7:992–999. (SCI, IF 4.5)

35. Jian-Hao Wang, Hai-Qiao Wang, Hai-Li Zhang, Xiu-Qing Li, Xiao-FengHua, Yuan-Cheng Cao, Zhen-Li Huang, Yuan-Di Zhao*, Purification of denaturedbovine serum albumin coated CdTe quantum dots for sensitive detection ofsilver(I) ions, Analytical andBioanalytical Chemistry, 2007, 388: 969–974. (SCI, IF 3.778)

34. Jian-Hao Wang,Hai-Qiao Wang, Yong-Qiang Li, Hai-Li Zhang, Xiu-Qing Li, Xiao-Feng Hua,Yuan-Cheng Cao, Zhen-Li Huang and Yuan-Di Zhao*, Modificationof CdTe quantum dots as temperature-insensitive bioprobes, Talana, 2008, 74:724–729. (SCI, IF 3.498)

33. Jianhao Wang, Pengju Jiang, Lin Qiu, CheliWang, Jiang Xia*, Resolving antibody–peptide complexes withdifferent ligand stoichiometries reveals a marked affinity enhancement throughmultivalencyTalanta, 2013, 115:394–400(SCI, IF 3.498)

32. Jianhao Wang, PengjuJiang, Liqian Gao, Yongsheng Yu, Yao Lu,LinQiu, Cheli Wang, Jiang Xia*,Unique self-assembly properties of a bridge-shapedprotein dimer with quantum dots, J Nanopart Res, 2013, 15:1914(SCI, IF2.175).

31. Jianhao Wang,Lin Qiu, Cheli Wang, Yue Zhang, Jingyan Li, Jiang Xia* and Pengju Jiang *, ProbingAntigen-Antibody Interaction Using Fluorescence Coupled CapillaryElectrophoresis,Int. J. Mol. Sci. 2013, 14, 19146-19154(SCI, IF 2.464)

30. Lin Qiu, Yanhua Bi, Cheli Wang, Jingyan Li,Peilin Guo, Jinchen Li, Weijiang He, JianhaoWang*, and PengjuJiang*, Protein A Detection Based on Quantum Dots-Antibody Bioprobe UsingFluorescence Coupled Capillary Electrophoresis,Int.J. Mol. Sci.2014, 15,1804-1811 (SCI, IF 2.464)

29. JianhaoWang, Jingyan Li, Yiwan Teng,Wei Hu, Hong Chai, Jinchen Li, Cheli Wang, LinQiu*, Pengju Jiang*, Studies on multivalent interactions of quantumdots–protein self-assemble using fluorescence coupled capillaryelectrophoresis, J Nanopart Res,2014, 16:2487

28. Jianhao Wang,Jingyan Li, Lin Qiu, Jiang Xia, Pengju Jiang*, Implication for HLA-DQ2Mediated Antigen Presentation in Celiac disease, Clinical and Experimental Pharmacology and Physiology,2013, 40 (Suppl. 1), 35-36 (SCI, IF2.16).

27. Jian-Hao Wang1, Hai-Li Zhang1,Yong-Qiang Li, Jiao-Ru Qian, Hai-Qiao Wang, Ting-Ting Xuand Yuan-Di Zhao*, A feasible method of improving the quantumyield of CdTe/CdS quantum dots by the first heating–cooling cycle and theirapplication in cancer cell recognitionJ Nanopart Res, 2010, 12:1687–1695 (SCI,IF 2.175)

26. Jian-Hao Wang, Hai-Qiao Wang, Hai-Li Zhang, Xiu-Qing Li, Xiao-FengHua, Zhen-Li Huang, Yuan-Di Zhao*,Photoluminescenceenhancement by coupling of ovalbumin and CdTe quantum dots and its applicationas protein probe, ColloidSurface A, 2007, 305: 48–53. (SCI, IF 2.236)

25. Jian-Hao Wang1, Tian-Cai Liu1, Yuan-ChengCao, Xiao-Feng Hua, Hai-Qiao Wang, Hai-Li Zhang, Xiu-Qing Li, Yuan-Di Zhao*, Fluorescence resonance energy transferbetween FITC and water-soluble CdSe/ZnS quantum dots, Colloids Surface A, 2007,302:168–173. (SCI, IF 2.236)

24. Jian-Hao Wang1, Yong-Qiang Li1, Hai-Li Zhang,Hai-Qiao Wang, Song Lin, Jun Chen, Yuan-Di Zhao*, Qing-Ming Luo, Bioconjugationof concanavalin and CdTe quantum dots and the detection of glucose, Colloid Surface A, 2010,364:82–86. (SCI, IF 2.236)

23. Wang JianHao, Li ZhiJie, Qiu Lin, et al. Homing peptide conjugatedquantum dots for colorectal cancer imaging (in Chinese). Chin Sci Bull (科学通报中文版), 2013, 58: 556-560.

王建浩、李志杰、邱琳、王车礼、蒋鹏举*、曹之宪、夏江,基于靶向多肽的量子点探针用于结肠癌肿瘤组织识别,《科学通报》201358卷第7期:556-560 .

22. Yong-Qiang Li, Jian-Hao Wang, Hai-Li Zhang, Jie Yang,Li-Yun Guan, Hong Chen, Qing-Ming Luo and Yuan-Di Zhao*, High-sensitivityquantum dot-based fluorescence resonance energy transfer bioanalysis bycapillary electrophoresis, Biosensors and Bioelectronics, 2010, 25:1283–1289. (SCI, IF 5.602)

21. Qiao Xu, Jian-Hao Wang, Zhan Wang, Zhao-Hui Yin, Qin Yang, Yuan-Di Zhao*, Interaction of CdTe quantum dots with DNA, Electrochemistry Communications, 2008, 10:1337–1339. (SCI, IF 4.859)

20. Tian-Cai Liu, Jian-Hao Wang, Hai-Qiao Wang, Hai-Li Zhang, Zhi-Hong Zhang,Xiao-Feng Hua, Yuan-Cheng Cao, Yuan-Di Zhao*, Qing-Ming Luo, Bioconjugaterecognition molecules to quantum dots as tumor probes, Journal of BiomedicalMaterials Research: Part A, 2007, 83:1209–1216. (SCI, IF 2.625)

19. Hai-Qiao Wang, Jian-HaoWang, Yong-Qiang Li, Xiu-QingLi, Tian-Cai Liu, Zhen-Li Huang and Yuan-Di Zhao*, Multi-color encoding of polystyrene microbeads with CdSe/ZnS quantum dotsand its application in immunoassay, Journal of Colloid and InterfaceScience, 2007, 316: 622–627. (SCI, IF 3.07)

18. Zhan Wang, Jian-Hao Wang, Qiao Xu,Qin Yang, Xiao-Yu Zhang and Yuan-Di Zhao, Evaporative deposition of lipophilic quantum dots for anenzyme modified electrode,Microchimica Acta, 2009, 166: 133–138. (SCI, IF 3.033)

17. Qiao Xu, Jian-Hao Wang, Zhan Wang, Hai-Qiao Wang, QinYang,Yuan-Di Zhao*, Biosensor for Hydrogen Peroxide Based on Chitosan andNanoparticle Complex Film-Modified Glassy-Carbon Electrodes,AnalyticalLetters, 2009, 42: 2496–2508. (SCI, IF 1.016)

16. Yong-Qiang Li, Li-Yun Guan, Jian-Hao Wang, Hai-Li Zhang, Jun Chen,Song Lin, Wei Chen, Yuan-Di Zhao, Simultaneous detection of dual single-basemutations by capillary electrophoresis using quantum dot-molecular beaconprobe, Biosensors and Bioelectronics, 2010, 26: 2317–2322 (SCI, IF 5.602)

15. Hai-Qiao Wang, Yong-Qiang Li, Jian-Hao Wang, Qiao Xu, Xiu-Qing Li,Yuan-Di Zhao*, Influence of quantum dot's quantum yield to chemiluminescentresonance energy transfer, Analytica Chimica Acta, 2008, 610: 68–73. (SCI, IF4.555)

14. Yong-Qiang Li, Hai-Qiao Wang, Jian-Hao Wang, Li-Yun Guan, Bi-FengLiu, Yuan-Di Zhao and Hong Chen, A highly efficient capillary electrophoresis-based methodfor size determination of water-soluble CdSe/ZnS core-shell quantum dots, Analytica Chimica Acta, 2009, 647: 219–225(SCI, IF 4.555)

13. Yao Lu, Jianpeng Wang, Jianhao Wang, Lin Wang, ShannonWing-Ngor Au and Jiang Xia*, Genetically Encodable Design of Ligand “Bundling”on the Surface of Nanoparticles, Langmuir, 2012, 28: 13788–13792. (SCI, IF4.186)

12. Tian-Cai Liu, Hai-Li Zhang, Jian-Hao Wang, Hai-Qiao Wang, Zhi-HongZhang, Xiao-Feng Hua,Yuan-Cheng Cao, Qing-Ming Luo, Yuan-Di Zhao*, Study onmolecular interactions between proteins on live cell membranes using quantumdot-based fluorescence resonance energy transfer, Analytical  and Bioanalytical  Chemistry, 2008, 391: 2819–2824.  (SCI, IF3.778)

11. Hai-Li ZhangYong-Qiang Li,Jian-Hao WangXiang-Ning LiSong Lin,Yuan-Di Zhao, and Qing-Ming Luo, Special method to prepare quantum dot probes with reducedcytotoxicity and increased optical property, Journal of Biomedical Optics,2010, 15: 015001. (SCI, IF 3.157)

10. Zhan Wang, Qiao Xu, Jian-Hao Wang, Qin Yang,Jiu-Hong Yu and Yuan-Di Zhao, Ascorbic acid biosensor based onlaccase immobilized on an electrode modified with a self-assembled monolayerand coated with functionalized quantum dots, Microchimica Acta, 2009, 165:387–392. (SCI, IF 3.033)

9. Hai-Li Zhang, Tian-Cai Liu, Jian-Hao Wang, Zhen-Li Huang,Yuan-DiZhao*, Qing-Ming Luo, Development of quantum dots in bioimaging, ChineseJournal of Analytical Chemistry, 2006, 34: 1491–1495. (SCI, IF 0.941)

8. Tian-Cai Liu, Zhen-Li Huang,Hai-Qiao Wang, Jian-Hao Wang,Xiu-Qing Li, Yuan-Di Zhao*, Qing-Ming Luo,Temperature-dependent photoluminescence of water-soluble quantum dots fora bioprobe, Analytica Chimica Acta, 2006, 559: 120–123. (SCI, IF 4.555)

7. Hai-Qiao Wang, Hai-Li Zhang,Xiu-Qing Li, Jian-Hao Wang, Zhen-LiHuang, Yuan-Di Zhao*, Solubilization and bioconjugation of QDs and theirapplication in cell imaging,Journal of Biomedical Materials Research:Part A, 2008, 86:833–841.  (SCI, IF 2.625)

6. Hai-Qiao Wang, Zhen-Li Huang,Tian-Cai Liu, Jian-Hao Wang,Yuan-Cheng Cao, Xiao-Feng Hua, Xiu-Qing Li, Yuan-Di Zhao*, A Feasible andQuantitative Encoding Method for Microbeads with Multicolor Quantum Dots,Journal of Fluorescence, 2007, 17: 133–138. (SCI, IF 2.107)

5. Yuan-Cheng Cao, Zhan Wang,Hai-Qiao Wang, Jian-Hao Wang,Xiao-Feng Hua, Xin Jin, Liang Yang, Zhen-Li Huang, Man-Xi Liu, and Yuan-DiZhao*, Enhanced Optical Property of Au Coated Polystyrene Beads for Multi-ColorQuantumDots Encoding, Journal of Nanoscience and Nanotechnology, 2008, 8: 1–7.(SCI, IF 1.563)

4. Jianpeng Wang, Yunyu Nie, Yao Lu,Jiahui Liu, Jianhao Wang, Aisi Fu,Tiangang Liu, and Jiang Xia*, Assembly of Multivalent Protein Ligands andQuantum Dots: A Multifaceted Investigation,Langmuir, 2014, 30:2161–2169 (SCI, IF 4.186)

3. Hai-Qiao Wang, Tian-Cai Liu,Yuan-Cheng Cao, Zhen-Li Huang, Jian-HaoWang, Xiu-Qing Li, Yuan-Di Zhao*, A flow cytometricassay technology based on quantum dots encoded beads, Analytica Chimica Acta,2006, 580: 18–23. (SCI, IF 4.555)

2. Xiao-Feng Hua, Tian-Cai Liu,Yuan-Cheng Cao, Bo Liu, Hai-Qiao Wang, Jian-HaoWang, Zhen-Li Huang, Yuan-Di Zhao*, Characterization of the coupling of quantum dots andimmunoglobulin antibodies,Analytical  and  Bioanalytical  Chemistry, 2006, 386: 1665–1671.(SCI, IF 3.778)

1. Xiao-Xia Zhu, Yuan-Cheng Cao, XinJin, Jie Yang, Xiao-Feng Hua, Hai-Qiao Wang, Bo Liu, ZhanWang, Jian-Hao Wang, Liang Yang and Yuan-DiZhao*, Optical encoding of microbeads based on silica particle encapsulatedquantum dots and its applications, Nanotechnology, 2008, 19: 025708. (SCI,IF 3.979)

  

申请专利30项,已授权5

部分专利:

1.赵元弟,王建浩,一种提高量子点生物探针环境温度稳定性的方法,申请号:200810197230.6

2.王建浩,王车礼,邱琳,蒋鹏举,一种毛细管电泳荧光检测装置(实用新型),申请号:201220489399.0 (授权)

3.赵元弟,王建浩,一种制备高性能水溶性量子点的方法,申请号:200810197229.3

4.赵元弟,李永强,王建浩,朱晓霞,一种对悬浮阵列中微球进行编码的方法,申请号:200910306758.7

5.王建浩,王车礼,蒋鹏举,邱琳,夏江,一种用于结肠癌肿瘤组织识别的量子点靶向探针及其制备方法,申请号:201210433341.9

6.王建浩,邱琳,蒋鹏举,王车礼,一种基于量子点多肽复合物的荧光毛细管电泳检测凝血酶活性的方法,申请号201210367070.1

7.王建浩,邱琳,蒋鹏举,王车礼,夏江,检测量子点与生物分子相互作用的液滴微流控系统及方法,申请号:201210356962.1(授权)

8.王建浩,邱琳,蒋鹏举,王车礼,夏江,一种修饰量子点的新型多肽配体,申请号: 201210355363.8

9.王建浩,邱琳,王车礼,蒋鹏举,夏江,一种多肽纳米金粒子药物载体合成方法,申请号:201210391541.2

10.王建浩,王车礼,邱琳,蒋鹏举,夏江,一种毛细管电泳检测抗体与多肽相互作用的方法,申请号:201210390038.5

11.王建浩,邱琳,蒋鹏举,王车礼,夏江,一种毛细管电泳检测蛋白多肽相互作用的方法,申请号:201210390082.6

12.王建浩,王车礼,蒋鹏举,邱琳,夏江,一种量子点标记蛋白的方法,申请号: 201210431798.6

13.王建浩,王车礼,邱琳,蒋鹏举,一种毛细管电泳荧光检测装置,申请号:201210354973.6

14.王建浩,蒋鹏举,邱琳,王车礼,李静燕,郭沛霖,夏江,一种量子点标记纳米带蛋白的方法,申请号:201310428686.X (授权)

15.王车礼,刘高伟,姚超,王建浩,曾桂凤,周永生,李为民,一种粘土基C22-环脂肪三酸酯合成用催化剂及其制备方法,申请号:201410008464.7

16.王建浩,李进晨,曹之宪,李明星,邱琳,蒋鹏举,一种维生素D与奥美拉唑复合物及其偶联方法,申请号:201510661089.0

17.王建浩,蒋鹏举,邱琳,王车礼,李静燕,郭沛霖,李进晨,夏江,一种量子点标记蛋白聚合物的方法,申请号:201310429977.0(授权)

18.王车礼,刘高伟,姚超,王建浩,曾桂凤,周永生,李为民,吴康,一种凹凸棒石粘土基环加成反应催化剂的制备方法,申请号:201410046943.8

19.王建浩,李静燕,滕一万,蒋鹏举,邱琳,王车礼,柴宏,秦玉琴,李进晨,一种量子点生物探针检测多肽电荷数的方法,申请号:201410217443.6

20.王建浩,蒋鹏举,邱琳,李静燕,滕一万,王车礼,秦玉琴,李进晨,一种毛细管内蛋白-量子点相互作用的检测方法,申请号:201410444544.7

21.王建浩,李静燕,蒋鹏举,邱琳,李进晨,王车礼,秦玉琴,滕一万,柳丽,周翔,一种含不饱和羰基的药物小分子的制备方法,申请号:201410769207.5

22.王建浩,李进晨,蒋鹏举,邱琳,李静燕,王车礼,秦玉琴,滕一万,柳丽,周翔,利用酯键断裂释放药物的方法,申请号:201410769227.2

23.王建浩,李静燕,蒋鹏举,邱琳,李进晨,王车礼,秦玉琴,柳丽,滕一万,一种检测量子点-蛋白结合动力学的方法,申请号:201510129253.3

24.王建浩,李进晨,柴宏,张晨澄,陈瑶,滕一万,蒋鹏举,邱琳,王车礼,柳丽,杨丽,樊杰,刘菲菲,一种快速检测量子点与HAT标签相互作用的方法,申请号201510560728.4

25.王建浩,刘菲菲,滕一万,陈瑶,蒋鹏举,邱琳,李静燕,李进晨,王车礼,杨丽,张晨澄,樊杰,柳丽,一种检测量子点表面多肽数量的方法,申请号:201510561217.4

26.王建浩,顾亚琴滕一万,陈瑶,蒋鹏举,邱琳,李进晨,王车礼,杨丽,樊杰,刘菲菲,柳丽,一种毛细管内检测酶动力学的方法,申请号:201510561382.X

27.王建浩,李进晨,柳丽,蒋鹏举,邱琳,杨丽,樊杰,程永江,吴昊,董冰玉,孙凯,谢雨佳,蒋雨,一种结肠癌核磁共振多功能造影剂的制备方法,申请号:201510660787.9

28.王建浩,李进晨,陈瑶,滕一万,蒋鹏举,邱琳,王车礼,张晨澄,杨丽,顾亚琴,刘菲菲,董冰玉,一种快速检测蛋白酶Jmjd6与量子点结合速率的方法,申请号:201510560830.4

29.王建浩,秦玉琴,滕一万,陈瑶,李进晨,蒋鹏举,邱琳,王车礼,杨丽,张晨澄,樊杰,柳丽,一种毛细管电泳快速检测碱基不匹配数量的方法,申请号:201510559851.4
 30. 
王建浩,张晨澄,陈瑶,滕一万,蒋鹏举,邱琳,李静燕,李进晨,王车礼,杨丽,樊杰,刘菲菲,柳丽,一种毛细管内快速检测酶浓度的方法,申请号:201510559191.X

31.王建浩,李进晨,柴宏,张晨澄,陈瑶,滕一万,蒋鹏举,邱琳,王车礼,顾亚琴,杨丽,樊杰,董冰玉,一种基于毛细管电泳快速检测谷胱甘肽浓度的方法,申请号:201510560771.4

获奖:

2013 常州市第十二次自然科学优秀科技论文二等奖

2015首届常州大学青年标兵

2015常州市第十三次自然科学优秀科技论文二等奖